By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Research Scientific Director, Head of Small molecule Automation, is based in Cambridge, MA, within the R&D — Research division, specifically supporting Takeda’s Digital Discovery & Development Engine. This full-time Director-level role is instrumental in building and leading the automation of small molecule synthesis for Takeda’s “Lab of the Future” initiative to implement highly efficient, AI-integrated DMTA (Design–Make–Test–Analyze) cycles toward rapid and reliable small molecule discovery.

The Head of Small Molecule Automation leads the strategy, design, and execution of small molecule synthesis using fully automated, robotic platforms to accelerate decision-making across Takeda’s discovery portfolio by quickly and reliably generating compound sets for testing. The role collaborates closely with medicinal chemistry, in-vitro pharmacology, DMPK, data science/AI/computational chemistry, and automation engineering to ensure seamless integration of compound synthesis with AI-driven design, and includes integrating retrosynthetic planning, route design, and advanced chemical reaction miniaturization capabilities.

Accountabilities:

Define and execute the automation strategy for small-molecule synthesis, aligning platform capabilities with organizational discovery and development goals and the Lab of the Future roadmap.Prioritize and sequence automation investments in equipment, software, and talent based on scientific impact, throughput gains, and cost-to-value ratios.Promote the adoption of digital-first and automated approaches across the research community as a change champion.Establish a closed-loop DMTA vision by integrating robotics, digital data capture, and AI/ML to boost synthesis throughput, reduce cycle times, and enhance decision quality.Design end-to-end automated workflows for reaction scouting, parallel synthesis, scale-out, and purification (e.g., flash/Prep-HPLC) to ensure reproducibility and traceability.Standardize method libraries and digital SOPs, covering reaction templates, purification methods, and analytical routines, to enable rapid and consistent deployment across programs.Continuously evaluate and integrate new technologies such as liquid-handling robotics, continuous flow, microreactors, smart reactors, and generative chemistry tools.Accelerate DMTA cycles through high-throughput experimentation (HTE), parallel synthesis arrays, flow chemistry, and automated purification integrated with ELN/LIMS and scheduling/orchestration systems for efficient, low-touch labs.Establish and refine a vision for fully integrated workflows that encompass compound design, purification, QC data capture, analysis, and sample preparation for testing.Define, track, and report KPIs such as workflow efficiency, data accessibility, and cycle time improvements.Encourage method innovation, including novel reaction classes on automation, greener conditions, and continuous processing.Drive reliability engineering, preventive maintenance, and improvementsIntegrate EHS, machine safety, and cybersecurityEnsure up-time with scheduled maintenance, spares management, incident handling, and corrective action.Scale workflows from prototype to routine and maintain lab safety and compliance for automated operations.Oversee change control, validation, risk assessment, and conduct drills and post-mortems.Engage externally through contributions to patents, publications, and presentations that highlight platform advancements, and by active participation in consortia and conferences to share knowledge and gain insights to remain at the forefront of best practices.Contribute to data governance practices that promote longitudinal learning across Takeda’s discovery portfolio.Uphold Takeda’s values of Integrity, Fairness, Honesty, and Perseverance in all scientific and operational activities.

Education & Competencies (Technical and Behavioral):

Expected: Ph.D. in Organic or Medicinal Chemistry (or related field) with 10+ years of experience; or M.S. with 16+ years of experience; or B.S. with 18+ years of experience in pharmaceutical or biotech R&D, including small-molecule discovery.Deep medicinal chemistry knowledge, including SAR, SBDD, cheminformatics, and ADME/PK data interpretation.10+ years building and scaling lab or chemical process automation, and 5+ years leading cross-functional R&D teams.Proficiency with automated synthesis platforms, including robotic reaction screening, parallel synthesis, and purification systems.Experience with AI-driven DMTA and autonomous design-make loops and experiment planners.Familiarity with scheduling software, LIMS/ELN, and data pipeline tools used in automated labs.Strong leadership, managing and developing scientific teams at the senior scientist/principal scientist level.Exceptional written and verbal communication, with ability to influence at the Executive Director and VP levels.Demonstrated ability to drive change and transformation in complex, global R&D organizations.

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$177,000.00 - $278,080.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

OBJECTIVES/PURPOSE:

The Oncology (ONC) Therapeutic Area Lead in DMPK&M will have strong scientific and strategic leadership to impact broad responsibilities on the pipeline, talent, and strategy. This role will supervise and lead a team of DMPK&M project representatives and Modeling & Simulation (M&S) scientists responsible for delivering on Takeda’s research pipeline in the ONC therapeutic area.

This role is responsible for oversight on the DMPK&M strategy of the ONC portfolio and ensures the execution of DMPK&M project plans, translation, and dose optimization strategies, as well as review of regulatory filings.

This role will participate in therapeutic area-driven discussions and partner with cross-functional stakeholders to align on Takeda’s strategic framework. Key deliverables will be contributing to portfolio strategy and global business operations within DMPK&M. 

Demonstrates leadership experience in guiding talented teams and is a key member of the Global DMPK&M leadership team that drives department strategy, creates a positive and effective department culture, and strengthens partnerships across the Research and Development organizations within Takeda.

Leads a team of DMPK project representatives and modeling scientists who have key scientific and strategic input to research projects to enable Takeda to meet its global research goals.

Accountable for strategic planning and scientific oversight of the discovery and development portfolio for the ONC therapeutic area.

Actively supports DMPK&M Head in strategic execution of DMPK&M Vision and Mission.

Drives the development of organizational culture and capabilities by building strong alliances across the Research and Development organizations within Takeda.

Scientific responsibilities:

Provides scientific leadership and strategic guidance on stage-appropriate questions related to DMPK&M to ensure the selection and development of clinical candidates with optimal drug development characteristics.

Builds and enhances an external network to keep a pulse on scientific developments, novel strategies, partnership opportunities, and the latest competitive and regulatory landscape, particularly in relation to the ONC therapeutic areas.

Advises, reviews, and approves, on behalf of DMPK&M, milestone presentations and PRC narratives. Oversees and participates in regulatory activities, including the review and approval of robust and fit-for-purpose submission packages in the ONC therapeutic area.

Strategic responsibilities:

Act as the DMPK&M functional representative in governance committees and discussions regarding prioritization, strategy, resources, timelines, and decision-making criteria.

As the DMPK&M ONC Therapeutic Area Lead, this role will facilitate the alignment of DMPK&M strategy with DDU and TAU portfolio goals.

Collaborate with DDU and TAU senior leaders, communicating needs, strategy, and execution plans, while consulting with DMPK leadership to ensure resources and goals are aligned.

Accountable for appropriate resourcing of project support by collaborating with the Global DMPK&M leadership team.

Resources and reviews in-licensing evaluations for their respective therapeutic area. 

Management responsibilities:

Actively attract, develop, and retain talent.

DIMENSIONS AND ASPECTS:

Technical/Functional (Line) Expertise

Comprehensive understanding of drug discovery and development, the pharmaceutical industry, DMPK&M science.

Leadership

Achieves success for Takeda by collaboratively working with partners across the organization.

Ability to work across functions, regions, and cultures.

Functional level leadership with the ability to inspire, motivate and drive results.

Excellent communicator can persuasively convey both ideas and data, verbally and in writing.

Proven skills as an effective team player who can engender credibility and confidence within and outside the company.

Ability to distill complex issues and ideas down to simple comprehensible terms.

Demonstrates leadership presence and confidence.

Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors for the organization.

Builds teams across functions and geographies with individuals who have the right skills and experience to deliver on key organizational initiatives.

Invests time in helping others to enhance their skills and perform at a higher level.

Decision-making and Autonomy

Provides input to highly complex decisions that impacts functional area.

Accountable for decision making for designated function.

Ability to seek diverse input from multiple constituents and stakeholders to drive innovative solutions.

Ability to incorporate feedback and ensure decisions are implemented swiftly to yield flawless execution.

Accountable for providing input to and implementing vision and strategy for designated scope.

Interaction

Effectively navigates the changing external and internal environment and leads others through change by creating an inspiring and engaging workplace.

Cultivates a broad network of relationships throughout Takeda, with affiliates and external partners, in the industry and area of expertise.

Effectively represents function in negotiations with the ability to resolve conflict in a constructive manner.

Ability to build strong relationships and collaborate effectively with other interfacing Takeda functions.

Innovation

Forward thinking with the ability to recommend, influence on behalf of DMPK&M and implement continuous innovation.

Comfortable challenging the status quo and bringing forward innovative solutions.

Ability to take risks implementing innovative solutions, accelerating time to market.

Complexity

Ability to work in a global ecosystem (internal and external) with a high degree of complexity.

Ability to see and understand a broader, enterprise level perspective.

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

PhD degree in a scientific discipline with 15+ years experience, MS with 21+ years experience, or BS with 23+ years experience including at least 9 years of Industry experience in pharmaceutical DMPK and modeling

Good understanding of the (NS, ONC or ONC) DDU/TAU project portfolio, disease indications, and typical DMPK&M considerations for patients

Deep drug discovery and development experience and profound DMPK&M expertise required.

Experience in managing preclinical scientists and preparation of INDs, CTDs, NDAs, and MAAs.

Proactive, innovative, with good problem-solving skills.

Exceptional leadership, coaching, employee development skills.

Ability to work strategically in a cross functional team and matrix environment.

In-depth knowledge of the functional area, business strategies, and the company’s goals.

Excellent written, presentation, and verbal communication skills.

A track record of sustained, significant scientific contributions in DMPK and modeling, as demonstrated by publications and presentations.

This position is currently classified as “ hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$212,000.00 - $333,190.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Senior Scientist will play a pivotal role in Takeda’s “Lab of the Future” initiative, driving the design, miniaturization, and execution of robust bioanalytical assays on fully automated, integrated platforms. Leveraging advanced automation systems and statistical analysis, this individual will ensure high-throughput, reproducible, and high-quality data generation to support iterative AI-integrated Design–Make–Test–Analyze (DMTA) cycles for both small- and large-molecule discovery. The Senior Scientist will partner closely with DMPK, medicinal chemistry, data sciences, and automation engineering to translate complex bioanalytical data into actionable insights that accelerate portfolio progression and enable data-driven decision-making. This role contributes to critical function delivery as follows:

Accelerates Discovery through Automation and AI-Integrated DMTA: Designs and executes bioanalytical assays in 384- and 1,536-well formats on fully automated, robotic platforms with integrated workflows, enabling rapid, high-throughput testing and iterative optimization.Ensures Data Quality and Scientific Rigor: Applies statistical methodologies to evaluate assay performance (e.g., Z’ factor, variability metrics, curve-fit confidence) and maintains reproducibility and reliability of decision-enabling datasets.Drives Cross-Functional Impact: Partners with DMPK, medicinal chemistry, and data science teams to interpret bioanalytical data in the context of SAR, disease biology, and mechanism-of-action, informing compound progression and portfolio decisions.

Accountabilities:

Advance Automated Bioanalytical Lead Profiling

Design, develop, optimize, and validate bioanalytical assays supporting hit identification, hit-to-lead, and lead optimization programs for small and large molecules.Drive assay miniaturization to 384- and 1,536-well formats, ensuring robustness, reproducibility, and biological relevance.Implement statistically rigorous assay performance standards (e.g., Z’ factor, signal-to-background, CV, curve-fit quality metrics) to ensure data integrity and confidence in decision-making.

Enable Efficient DMTA Cycles

Execute DMTA lead profiling assays, ensuring reliable, timely delivery of high-quality MS data across small- and large-molecule modalities.Adapt and translate bioanalytical assays to high-throughput MS platforms (e.g., Acoustic MS, RapidFire MS, MALD-MS or other).Continuously improve workflows to shorten cycle times and increase throughput while maintaining quality.

Operate Within Fully Integrated, Automated Systems

Develop and execute assays on fully automated robotic platforms, including liquid handling systems, acoustic dispensing, and multimode detection technologies.Partner with automation engineers to design scalable, modular workflows aligned with Lab of the Future principles.Contribute to seamless integration of instrumentation with LIMS/ELN systems, scheduling software, and digital data pipelines to enable end-to-end automation.

Ensure Data Excellence & AI-Readiness

Apply advanced statistical analysis and visualization tools to assess assay robustness, variability, and data quality.Ensure datasets are standardized, curated, and appropriately annotated to support AI/ML-driven analytics and cross-program insights.Contribute to data governance practices that promote longitudinal learning across Takeda’s discovery portfolio.

Collaborate Across Takeda

Partner closely with DMPK, medicinal chemistry, data sciences, and translational sciences to advance program objectives.Communicate findings clearly in cross-functional forums and contribute to scientific discussions that shape portfolio decisions.Uphold Takeda’s values of Integrity, Fairness, Honesty, and Perseverance in all scientific and operational activities.

Education & Competencies (Technical and Behavioral):

Expected: Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline with at least 2+ years of industry experience; OR M.S. with 8+ years; OR B.S. with 10+ years of relevant experience with pharmaceutical or biotech R&D.Deep hands-on expertise in high-throughput MS (e.g., acoustic MS, RapidFire MS, MALDI-MS or other platforms), with a track record of developing and running high-throughput MS assays.Proven expertience working with DMTA or screening workflows.Working knowledge of integrated HTS automation systems and robotic platforms, including programming, configuring, and troubleshooting liquid handlers (e.g., Echo, Hamilton, Beckman, Agilent).Hands-on familiarity with scheduling software, LIMS/ELN, and data pipeline tools commonly used in automated labs.Proficiency with MS data analysis tools and software; experience with scripting or data handling (e.g., Python, R, Spotfire) is a plus.Demonstrated ability to work independently and collaboratively in a highly matrixed, cross-functional environment while managing multiple priorities and contribute to mentoring or guiding junior scientific staff.

Proven track record of:

Developing and validating bioanalytical assays for drug discovery.Adapting bioanalytical assays to high-throughput MS platforms; including miniaturization, and automation-friendly assay design.Experience in high-content, high-throughput environments, including design-of-experiments (DoE) approaches for optimization.Familiarity with LIMS/ELN systems and data pipeline tools.Running assays on fully automated, robotic platforms in high-throughput environments.Successful miniaturization of assays to at least 384-well and preferably 1,536-well plate formats.

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA. 

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Objective / Purpose:  

The Director, Target Validation Sciences will lead a next-generation, automation-enabled assay hub for human disease–relevant target validation. Working closely with the Lab of Tomorrow (Takeda’s lab automation and digitalization initiative), this role will transform how target validation is conducted by integrating advanced 3D disease models, organ-on-a-chip technologies, automation, and AI-enabled data analytics into scalable, decision-driving platforms. 

This role will contribute to and help shape the scientific direction of target validation across therapeutic areas, modernize workflows through digitalization, and support assay transfer across functions while driving the standardization and centralization of assay platforms, accelerating portfolio progression. 

Accountabilities:  

Establish and grow a center of excellence for human disease–relevant assay platforms, integrating advanced 3D tissue culture systems, organ-on-chip technologies, and automation-enabled approaches to support scalable target validation. Own and drive cross-functional assay transfer and standardized workflows (including SOP frameworks), partnering with platform teams to ensure reproducibility, scalability, and data quality across target validation platforms. Provide scientific and strategic leadership in target validation for GI inflammatory/fibrotic diseases, oncology, and Neuroscience, including development of novel, disease-relevant assays that translate mechanistic biology into decision-driving data and enable pipeline progression. Partner closely with the Lab of Tomorrow, as well as Computer Science and Data Science teams, to integrate automation-enabled workflows, AI-driven analytics, and computational approaches into scalable target validation platforms. Align target validation strategies with portfolio priorities across Boston and Shonan sites, contributing to TVS leadership discussions and establishing best practices. Influence target progression through rigorous data interpretation and sound scientific judgment. Build and develop a high-performing scientific team while ensuring quality and compliance standards supporting IND-enabling activities where applicable. 

Education & Competencies:  

PhD required in Immunology, Molecular/Cell Biology, Pharmacology, or related discipline with 6+ years of biopharmaceutical industry experience. Strong expertise in GI inflammatory and fibrotic biology (including IBD) and/or oncology. Demonstrated success in mechanism-based target validation and human disease–relevant assay development (e.g., 3D tissue culture systems, complex cellular models). Deep experience leading cell-based assay development for scalable target validation platforms, including assay design at the appropriate well scale and optimization for robustness, reproducibility, and transferability to automated environments. Experience partnering with Computer Science and Data Science teams and leveraging AI-enabled analytics to inform biological decision-making. Proven people leadership and cross-functional influence in a matrix environment. Strategic thinker with strong scientific judgment and communication skills. 

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$177,000.00 - $278,080.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Associate Director will play a pivotal role in Takeda’s “Lab of the Future” initiative, building a capability to provide robust cell lines, at scale, to enable the execution of robust cellular assays on fully automated, integrated platforms. The Associate Director will partner closely with Drug Discovery Units (DDUs), Lead Profiling, and automation engineering to design, build and leverage an automated infrastructure to supply cells to scientists running assays to drive Takeda’s DMTA cycle. In this role you will:

Accelerate Discovery through Automation and AI-Integrated DMTA: Support the design and execution of cellular assays in 384- and 1,536-well formats on fully automated, robotic platforms with robust processes to ensure delivery of consistent cells through continuous culture or cryopreservation.Build a team and infrastructure that operates in a highly efficient way, leveraging state-of-the-art automation and technology.Drives Cross-Functional Impact: Partners with DDUs, Lead Profiling, and data science teams to interpret cellular data in the context of SAR, disease biology, and mechanism-of-action, informing compound progression and portfolio decisions.

Accountabilities:

     

Advance Automated Cell Culture

Define and lead the strategy for design, development, and deployment of scalable cellular automation platforms to enable continuous culture and enterprise-level cell banking.Drive cross-functional alignment with assay development teams to enable robust miniaturization to 1,536-well formats, ensuring reproducibility, scalability, and biological relevance across automated workflows.

Drive Quality and Efficiency

Establish and oversee quality frameworks for cell line QC, banking, and lifecycle management to ensure consistency and reproducibility at scale.Leverage automation to minimize manual culture and support an assay environment that runs 24/7Define selection criteria for disease-relevant cellular models to ensure strong alignment with SAR and translational biology objectives.Contribute to seamless integration of instrumentation with LIMS/ELN systems, scheduling software, and digital data pipelines to enable end-to-end automation.

Ensure Data Excellence & AI-Readiness

Apply advanced statistical analysis and visualization tools to assess assay robustness, variability, and data quality.Ensure datasets are standardized, curated, and appropriately annotated to support AI/ML-driven analytics and cross-program insights.Contribute to data governance practices that promote longitudinal learning across Takeda’s discovery portfolio.

Collaborate Across Takeda

Partner closely with DDUs, data sciences, translational sciences, and medicinal chemistry to advance program objectives.Communicate findings clearly in cross-functional forums and contribute to scientific discussions that shape portfolio decisions.Uphold Takeda’s values of Integrity, Fairness, Honesty, and Perseverance in all scientific and operational activities.

Education & Competencies (Technical and Behavioral):

Ph.D. in Cell Biology, Pharmacology, Oncology, Chemical Biology, or related discipline with at least 6+ years of industry experience ORM.S. with 12+ years; OR B.S. with 14+ years of relevant pharmaceutical or biotech R&D experience.Deep expertise in cell biology, automated cell culture, and biobanking at scale, including primary, iPSC-derived, and engineered cell systemsSignificant experience in design and deployment of fully integrated, end-to-end automated cell culture and assay platforms to support high throughput workflowsHands-on experience developing, optimizing, and executing High Content Assays, with familiarity in other assay modalities such as reporter gene, CTG, GPCR, HTRF, AlphaScreen, MSD, and qPCR for primary, secondary, and mechanistic profiling.Working knowledge of integrated HTS automation systems and robotic platforms, including programming, configuring, and troubleshooting liquid handlers (e.g., Echo, Hamilton, Beckman, Agilent).Demonstrated experience integrating AI/ML-driven analytics into DMTA workflows and decision-making.Ability to leverage data science to link cell health, assay performance, and SAR insightsHands-on familiarity with scheduling software, LIMS/ELN, and data pipeline tools commonly used in automated labs.Proficiency in data analysis and figure generation using tools such as Dotmatics, Spotfire or GraphPad.Demonstrated ability to work independently and collaboratively in a highly matrixed, cross-functional environment while managing multiple priorities and contribute to mentoring or guiding junior scientific staff.

Prove track record of:

Building and deploying end-to-end cellular automation platforms supporting high-throughput screening (384/1536 formats)Establishing fit-for-purpose QC frameworks (cell identity, passage control, phenotypic stability, contamination)

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$154,400.00 - $242,550.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

$10,000 Sign on bonus for External Candidates

 

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative health care leader and multi-specialty group practice, delivering an effective, connected system of care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our entire team of providers (physicians, AP/NPs and ancillary clinicians) works collaboratively with a value-based philosophy within our group practice as well as with hospitals, rehab and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

As the Vascular Technologist, you will perform noninvasive vascular testing procedures in accordance with established policies and protocols.  

Primary Responsibilities:

Prepares and positions patients for diagnostic imaging proceduresExplains procedures and process to patientsMoves imaging equipment into the specified position; determines exposure factors based on height, weight, the portion of the body involved, and the degree of penetration required; and adjusts equipment controls to set exposure factors and produce images of proper detail, density, and accuracyPractices radiation protection techniques to minimize radiation to patients and staffPerforming Vascular studiesPerform qualitative and quantitative analysis of data and preliminary report
 

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

Associate's degree in health care related fieldRegistered Vascular Sonographer (RVS) or Registered Vascular Technician (RVT) by American Registry of Diagnostic Medical Sonographers (ARDMS)American Heart Association Basic Life Support (BLS)Ability to provide CEU documentation for certification1+ years of experience from a vascular testing training program or certification course, such as an internship or practicumComputer experience with the ability to use word processing and spreadsheet programs. Electronic medical record (EMR) experience and/or aptitude to master the EMR based on other technology experience

Preferred Qualifications:

Bachelor's degree in related fieldDemonstrates solid interpersonal, organizational, and decision-making skillsProven ability to work independently and take initiative 

 

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The hourly pay for this role will range from $28.94 to $51.63 per hour based on full-time employment. We comply with all minimum wage laws as applicable.

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

 

OptumCare is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

 

OptumCare is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative health care leader and multi-specialty group practice, delivering an effective, connected system of care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our entire team of providers (physicians, AP/NPs and ancillary clinicians) works collaboratively with a value-based philosophy within our group practice as well as with hospitals, rehab and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

 

Position Details:

Location: Kenmore - 133 Brookline Avenue, Boston, MA, 02215

Department: Radiology - Mammography

Schedule: Full time, 18 hours/weekly, Friday 7:00am-5:30pm and Saturday 7:00am-3:30pm

 

As a Mammography Technologist I you will work under the guidance of a radiologist, perform mammography exams in accordance with MQSA, state regulations, and with health centers' established policies and procedures.

Primary Responsibilities:

Confirms appropriate clinical data, obtains patient history, and uses the lowest possible dose to provide high quality images for the interpreting radiologistProvides for the emotional, physical well-being, and safety of the patient while maintaining strict standards of patient confidentialityCommunicate effectively with patients as well as other members of the health care teamRecognizes and effectively communicates equipment problems in a timely manner to the Department SupervisorFor every location worked, provides on-going CEU documentation to support licensure requirementContinuing education and continuing experience requirements as defined by the American Registry of Radiologic Technologists (ARRT) must be maintainedWillingness to cover in other location(s) when urgent need arisesWillingness to participate in the training of new mammographers

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

High School diploma or equivalency certificate (e.g. GED, HiSET, TASC Test) from an accredited institution or governmental unitGraduate of an accredited radiography programMust be licensed in Radiography for 1+ yearsPassed the ARRT exam in Mammography

Must possess mammography license in the state of Massachusetts

 

Preferred Qualifications:

American Heart Association Basic Life Support (BLS)Advanced Cardiac Life Support (ACLS) may be required based on specialtyKnowledge of Mammography equipment and MQSA and ACR regulationsKnowledge of PACS and associated equipmentGeneral knowledge of healthcare delivery servicesProven ability to learn and master new tasks related to Image Quality and SafetyProven ability to communicate effectively and work with people of various diverse backgroundsProven ability to complete Mammography exams in a timely manner even under stressful condition
 

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The hourly pay for this role will range from $28.94 to $51.63 per hour based on full-time employment. We comply with all minimum wage laws as applicable.

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

 

 

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

UnitedHealth Group is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

External applicants are eligible for $10,000 sign on bonus!

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative health care leader and multi-specialty group practice, delivering an effective, connected system of care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our entire team of providers (physicians, AP/NPs and ancillary clinicians) works collaboratively with a value-based philosophy within our group practice as well as with hospitals, rehab and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

Position Details:

Location: Kenmore - 133 Brookline Avenue, Boston, MA 02215Department: RadiologySchedule: The following schedules are available - Full time, 40 hours/weekly, Wednesday, Friday, Saturday and/or Sunday, plus 1-2 additional weekdays, 8:30am - 5:00pm AND Full time, 40 hours/weekly, Monday through Friday 9:00am - 5:30pm OR Four 10-hour shifts Monday through Friday (flexible days)

As the Radiology Technologist, you will perform and assist in a variety of standard and specialized radiographic examinations and procedures. Demonstrates competency in all age groups and works in accordance with established policies and procedures.

Primary Responsibilities:

Works independently using extensive knowledge of anatomy, physiology, positioning, radiation physics and radiation dosageConfirms appropriate clinical data, obtains patient history and uses the lowest possible dose to provide high quality images for the interpreting radiologistProvides for the emotional, physical wellbeing and safety of the patient while maintaining strict standards of patient confidentialityPossesses the ability to communicate effectively with patients as well as other members of the health care teamUnderstands and is competent in other Radiology Department job responsibilities and performs these functions on a regular basisRecognizes and effectively communicates equipment problems in a timely manner to the Department SupervisorPerforms other duties as assigned

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

High School diploma or equivalency certificate (e.g. GED, HiSET, TASC Test) from an accredited institution or governmental unitGraduate of an accredited radiography program and registry eligibleLicensed in Massachusetts as a radiologic technologistCEU documentation required for licensure must be provided

Preferred Qualifications:

American Heart Association Basic Life Support (BLS)Advanced Cardiac Life Support (ACLS) may be required based on specialty1+ years of experience working as a radiology technologistKnowledge of Computed Radiography, Digital Radiography, Epic, Synapse, Pacsgear, answering phones and scheduling exams

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The hourly pay for this role will range from $23.41 to $41.83 per hour based on full-time employment. We comply with all minimum wage laws as applicable.

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

 

 

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

UnitedHealth Group is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

$5,000 Sign On Bonus for External Candidates

We offer excellent compensation, benefits within 30 days that include generous PTO, paid holidays, annual reviews, tuition reimbursement, along with opportunities for continued career progression!

 

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative health care leader and multi-specialty group practice, delivering an effective, connected system of care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our entire team of providers (physicians, AP/NPs and ancillary clinicians) works collaboratively with a value-based philosophy within our group practice as well as with hospitals, rehab and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

Under the direction of the department chief, nurse leader, or designee, the Special Procedure Nurse provides practice management support and direct patient care in a procedural unit. Responsibilities include pre- and post-procedure assessment, monitoring, and intra-procedural care for specialty areas such as GYN Surgery, Oral & Maxillofacial Surgery, Oncology, and GI procedures.  

 

Position Details:

Location: 133 Brookline Avenue, Boston, MADepartment: EndoscopySchedule: 40 Hours Weekly, 7AM - 5:30PM Days to be determined

Primary Responsibilities:

Support the procedural process as part of a collaborative care teamOrganize resources and activities to ensure safe, efficient procedural flowProvide specialty-specific care, including pre-op assessment, IV moderate sedation, intra-procedural support, and post-op monitoring for patients in areas such as GYN Surgery, Oral & Maxillofacial Surgery, and GI proceduresPerform nursing procedures within scope of practice (e.g., IV placement and medication administration, injections, wound care, EKGs, glucose testing)Deliver patient education and instructions for pre- and post-procedure care; maintain accurate documentation and confidentialityMonitor patient condition throughout the procedural process and communicate relevant data to the care teamAdminister medications per physician orders and assist with oncology care coordination and community resourcesMaintain compliance with safety standards, credentialing, and certifications (BCLS, ACLS, specialty certifications)Contribute to staff education, department meetings, and quality improvement initiativesServe as a resource for patient flow management and program planning; foster collaborative relationships

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

High School Diploma or equivalent Completed an accredited Registered Nurse education program Active and unrestricted RN licensure in the state of MA American Heart Association Basic Life Support (BLS) Advanced Cardiac Life Support (ACLS) may be required based on specialty. Must participate in IVMS (Intravenous Moderate Sedation) seminar every two years3+ years of relevant experience in medical/surgical or ambulatory nursing exceptions in consultation with VP of Nursing

Preferred Qualifications:

Bachelor of Science in Nursing (BSN) Experience with an electronic medical records system, EPIC experienced

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The hourly pay for this role will range from $43.63 to $81.04 per hour based on full-time employment. We comply with all minimum wage laws as applicable.

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

 

 

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

UnitedHealth Group is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative healthcare leader, delivering an effective system of connected care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our team of physicians, primary care providers and clinicians work with hospitals, community specialists and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

 

Position Details:

Location: Kenmore - 133 Brookline Avenue, Boston, MA 02215Department: Radiology - MammographySchedule: Part time, Every Other Saturday, 7:00am - 3:00pm

 

As a Mammography Technologist I you will work under the guidance of a radiologist, perform mammography exams in accordance with MQSA, state regulations, and with health centers' established policies and procedures.

 

Primary Responsibilities:

Confirms appropriate clinical data, obtains patient history, and uses the lowest possible dose to provide high quality images for the interpreting radiologistProvides for the emotional, physical well-being, and safety of the patient while maintaining strict standards of patient confidentialityCommunicate effectively with patients as well as other members of the health care teamRecognizes and effectively communicates equipment problems in a timely manner to the Department SupervisorFor every location worked, provides on-going CEU documentation to support licensure requirementContinuing education and continuing experience requirements as defined by the American Registry of Radiologic Technologists (ARRT) must be maintainedWillingness to cover in other location(s) when urgent need arisesWillingness to participate in the training of new mammographers

 

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

High School diploma or equivalency certificate (e.g. GED, HiSET, TASC Test) from an accredited institution or governmental unitGraduate of an accredited radiography programLicensed in Radiography for 1+ yearsPassed the ARRT exam in MammographyMust possess mammography license in the state of Massachusetts

 

Preferred Qualifications:

American Heart Association Basic Life Support (BLS)Advanced Cardiac Life Support (ACLS) may be required based on specialtyKnowledge of Mammography equipment and MQSA and ACR regulationsKnowledge of PACS and associated equipmentGeneral knowledge of healthcare delivery servicesProven ability to learn and master new tasks related to Image Quality and SafetyProven ability to communicate effectively and work with people of various diverse backgroundsProven ability to complete Mammography exams in a timely manner even under stressful condition

 

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The hourly pay for this role will range from $28.94 to $51.63 per hour based on full-time employment. We comply with all minimum wage laws as applicable.

 

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

 

 

OptumCare is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

 

OptumCare is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative health care leader and multi-specialty group practice, delivering an effective, connected system of care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our entire team of providers (physicians, AP/NPs and ancillary clinicians) works collaboratively with a value-based philosophy within our group practice as well as with hospitals, rehab and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

Position Details:

Location: 133 Brookline Avenue, Boston, MA 02215

Department: Radiology - MRI

Schedule: Part time, 16 hours/weekly, Every other weekend, Saturday and Sunday, 5:30am - 10:30pm (hours may be flexible)

As a MRI Technologist you will Performs magnetic resonance imaging procedures to aid physicians in the diagnosis of disease. Demonstrates excellent patient/staff communication skills.

Primary Responsibilities:

Lifts and positions patients, operates equipment, and administers contrast mediaDemonstrates knowledge of MRI safetyCompletes/reviews patient history on every patient prior to studyMonitors patient's condition during procedure and notifies physician of abnormalities; assists with first aid and CPR as necessaryDemonstrates proper filming procedure and critiques films to ensure accuracy and clarity for physician interpretation; helps to maintain laser printer and automatic processorProvides staff and patient protection in accordance with prescribed radiation safety standardsDemonstrates proper infection control practicesMaintains orderliness and cleanliness of work area; cleans CT and ancillary equipmentAssists with QA/QC activitiesDemonstrates the ability to work well with physicians and administrative support staff at all levelsTransports/escorts patients to and from areaMay instruct students and perform competency evaluation in CT and/or MRIAttends and participates in staff meetings and in-servicesServes as a resource to support staff to assure appropriate booking of studiesManages daily schedule to maximize thru-putWhen requested, speaks with patients re: their concerns prior to studyMonitors inventory. Assists with ordering and stocking of supplies necessary for imaging operations

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

High School diploma or equivalency certificate (e.g. GED, HiSET, TASC Test) from an accredited institution or governmental unitCertification as a CT/MRI TechnologistAdvanced Cardiac Life Support (ACLS) may be required based on specialtyRegistration with the American Registry of Radiologic Technologists required by the StateProven ability to analyze and solve complex technical problems requiring the use of basic technical principles plus in-depth, experienced-based knowledge

Proven good communication skills in order to explain instructions and procedures to patients, visitors and employees, to comfort patients and their families and to conduct formal classroom training programs

Preferred Qualifications:

American Heart Association Basic Life Support (BLS)2+ years of MRI scanning experience

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The hourly pay for this role will range from $28.27 to $50.48 per hour based on full-time employment. We comply with all minimum wage laws as applicable.

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

UnitedHealth Group is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

$10,000 Sign on bonus for External Candidates

 

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative health care leader and multi-specialty group practice, delivering an effective, connected system of care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our entire team of providers (physicians, AP/NPs and ancillary clinicians) works collaboratively with a value-based philosophy within our group practice as well as with hospitals, rehab and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

As the Nuclear Medicine - Team Lead, you will support the workflow of Nuclear Medical Technologists and support personnel. Performing and assisting in a variety of diagnostic and cardiac Nuclear Medicine examinations and procedures. You'll serve as a  functional supervisor or team leader for unit support staff.

Primary Responsibilities:

Serves as a skilled clinical/administrative support resource for team membersAssumes leadership duties while performing nonexempt support tasksEvaluates daily schedules and ensures coverage during absences Implements and adjusts operational procedures within established guidelinesGuides staff on workflow execution and suggests improvementsSupports performance reviews and monitors service quality (e.g., phone systems)Acts as point of contact for patient issues and may supervise in manager's absence

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

Certification as an NM Technologist (CNMT), Registration as a Technologist RT(N) credential with the American Registry of Radiologic Technologists (ARRT) or Nuclear Medicine Technologist Certification Board (NMTCB) CPR certification Advanced Cardiac Life Support (ACLS) may be required based on specialtyAbility to provide documentation of CEUs required for licensure2+ years of Nuclear Medicine scanning experience Thorough knowledge and understanding of nuclear medicine practices and procedures, typically acquired by 3+ years of broad based, multi-procedures, experience as an NM technologist

Preferred Qualifications:

Sound judgment with the ability to work and make decisions in a fast-paced environmentProven solid interpersonal skills with the ability to interact effectively with patients and medical professionals

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The hourly pay for this role will range from $44.09 to $78.70 per hour based on full-time employment. We comply with all minimum wage laws as applicable.
 

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

UnitedHealth Group is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

Explore opportunities at Atrius Health, part of the Optum family of businesses. We're an innovative health care leader and multi-specialty group practice, delivering an effective, connected system of care for adult and pediatric patients at 28 practice locations in eastern Massachusetts. Our entire team of providers (physicians, AP/NPs and ancillary clinicians) works collaboratively with a value-based philosophy within our group practice as well as with hospitals, rehab and nursing facilities. Be part of our vision to transform care and improve lives by building trust, understanding and shared decision-making with every patient. Join us and discover the meaning behind Caring. Connecting. Growing together.

 

As the Nutritionist, you will assess the nutritional problems and needs of patients, develop a nutrition treatment plan, and ensure the patient receives the necessary counseling and education regarding the specific dietary information. You'll consult with patients on both on-going and disease-specific nutrition needs. Provide follow-up as needed and files all necessary documentation related to treatment

 

Primary Responsibilities:

Conducts a nutrition assessment and obtains nutrition history from patient. Consults with physician and other clinician's to determine patient's nutritional needs and diet restrictions as neededScreens for potential nutrition riskDevelops and implements treatment plan in accordance with department guidelines for disease states managed by HVMA NutritionProvides individual counseling on the control of diabetes, cholesterol, hypertension, morbid obesity, and other diagnosisSuggests appropriate behavior modification methods for control and alteration of eating habitsWorks with referring clinician to integrate nutrition plan with other on-going healthcare needsEducates patients on nutritional needs and assesses patient's competence in understanding prescribed dietary principlesWorks with patient to establish goals and objectives to help meet nutrition planAppropriately documents all consultations and treatment plansMonitors patients' access to nutrition servicesServes as resource to other clinicians on nutritional careMaintains knowledge on nutrition research related to diagnosis seen, to ensure a high level of patient care and treatment

 

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications:

Master of Science in Nutrition Registered Dietician with the Commonwealth of Massachusetts license (RD)  Current registration with the American Dietetic AssociationAdvanced Cardiac Life Support (ACLS) may be required based on specialty3+ years of skills and experience in a medical environment and/or administering nutritional services Electronic medical record (EMR) experience and/or aptitude to master the EMR based on other technology experienceComputer experience with the ability to use word processing and spreadsheet programsDemonstrated solid interpersonal skills, including the ability to explain information clearlyDemonstrated team approach to work and experience partnering with other clinicians in providing care

 

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The salary for this role will range from $49,700 to $88,800 annually based on full-time employment. We comply with all minimum wage laws as applicable.

 

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

 

 

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

 

UnitedHealth Group is a drug-free workplace. Candidates are required to pass a drug test before beginning employment.

Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Associate Scientist will play a critical role in advancing cellular lead profiling and iterative Design–Make–Test–Analyze (DMTA) activities across oncology and gastrointestinal disease programs. Operating within fully automated, integrated laboratory systems, this individual will develop and execute robust cell-based assays that generate high-quality, decision-enabling data for small- and large-molecule discovery. With strong expertise in statistical analysis to assess assay robustness and data quality, the Associate Scientist will ensure rigor, reproducibility, and efficiency across programs. Importantly, this role will play a key part in Takeda’s “Lab of the Future” initiative, driving implementation of highly efficient, AI-integrated DMTA cycles that accelerate innovation and enhance data-driven discovery. This role contributes to critical function delivery:

Accelerates Discovery Through Automation & AI Integration: Implements and operates fully automated, end-to-end assay workflows integrated with AI-enabled analytics to increase throughput, reduce variability, and shorten DMTA cycle times.Ensures Data Quality & Scientific Rigor: Applies statistical methodologies to evaluate assay performance (e.g., Z’, variability metrics, curve-fit confidence) and ensures high-integrity data that directly informs compound progression and portfolio decisions.Drives Cross-Functional Impact: Partners closely with chemistry, data sciences, and early discovery teams to translate complex cellular data into actionable insights, supporting timely and informed advancement of discovery programs.

Accountabilities:

Develop, miniaturize, optimize, and validate robust cell-based assays to 384 or 1536 well plate formats to support lead optimization programs across oncology and gastrointestinal disease areas.Generate high-quality, reproducible data to enable informed decision-making within iterative Design–Make–Test–Analyze (DMTA) cycles.Design and execute high-content imaging and multiparametric cellular assays for compound characterization and mechanistic profiling.Perform and ensure timely execution of IC50/EC50 determinations and communicate results effectively to program teams.Apply rigorous statistical analysis, curve fitting, and data visualization tools to interpret complex cellular datasets.Utilize automation platforms and laboratory instrumentation to improve assay throughput, consistency, and efficiency.Incorporate AI-enabled tools and advanced software packages where appropriate to enhance data analysis and compound prioritization.Collaborate closely with cross-functional teams including chemistry, data sciences, and early discovery to drive project progression.Interpret, summarize, and present research findings at internal meetings and external scientific conferences as needed.Sustain a high-performing and reliable laboratory environment by rigorously applying quality control standards, executing preventative maintenance of instrumentation, and ensuring strict adherence to established standard operating procedures (SOPs).

Education & Competencies (Technical and Behavioral):

Expected: Master’s degree in in Cell Biology, Immunology, Oncology, Pharmacology, or related discipline with 3+ years OR Bachelor’s degree with 5+ years of relevant industry experience in drug discovery (pharma/biotech).Demonstrated expertise in:Mammalian cell culture (primary cells, engineered lines, co-culture systems, adherent and suspension cells)Cell-based potency assaysDose-response curve generation and IC50/EC50 analysisHigh-content imaging platformsExperience working within DMTA-driven discovery workflows.Strong data analysis and curve-fitting skills.Familiarity with laboratory automation systems.Excellent organizational and communication skills.Proven experience in developing and/or evaluating novel small molecule and biologicsStays current with emerging scientific literature, competitive landscapes, and innovative technologies

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$103,500.00 - $162,690.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Associate Scientist will play a critical role in advancing high-throughput mass spectrometry screening and iterative Design–Make–Test–Analyze (DMTA) activities across small and large molecule programs. Operating within fully automated, integrated laboratory systems, this individual will develop and execute robust bioanalytical assays that generate high-quality, decision-enabling data for small and large molecule discovery. With strong expertise in statistical analysis to assess assay robustness and data quality, the Associate Scientist will ensure rigor, reproducibility, and efficiency across programs. Importantly, this role will play a key part in Takeda’s “Lab of the Future” initiative, driving implementation of highly efficient, AI-integrated DMTA cycles that accelerate innovation and enhance data-driven discovery. This role contributes to critical function delivery:

Accelerates Discovery Through Automation & AI Integration: Implements and operates fully automated, end-to-end assay workflows integrated with AI-enabled analytics to increase throughput, reduce variability, and shorten DMTA cycle times.Ensures Data Quality & Scientific Rigor: Applies statistical methodologies to evaluate assay performance (e.g., Z’, variability metrics, curve-fit confidence) and ensures high-integrity data that directly informs compound progression and portfolio decisions.Drives Cross-Functional Impact: Partners closely with DMPK, medicinal chemistry, data sciences, and early discovery teams to translate assay data into actionable insights, supporting timely and informed advancement of discovery programs.

Accountabilities:

Develop, miniaturize, optimize, and validate robust high-throughput MS workflows, with a primary focus on acoustic MS, RapidFire MS, MALDI-MS or similar platforms for small and large molecule biotherapeutic lead profiling.Generate high-quality, reproducible data to enable informed decision-making within iterative Design–Make–Test–Analyze (DMTA) cycles.Design and execute quantitative and qualitative bioanalytical assays at 384- or 1536-well scalePerform and ensure timely execution of MS detection assays and communicate results effectively to program teams.Apply rigorous statistical analysis, curve fitting, and data visualization tools to interpret complex datasets.Utilize automation platforms and laboratory instrumentation to improve assay throughput, consistency, and efficiency.Collaborate closely with cross-functional teams including DMPK, medicinal chemistry, data sciences, and early discovery to drive project progression.Interpret, summarize, and present research findings at internal meetings and external scientific conferences as needed.Sustain a high-performing and reliable laboratory environment by rigorously applying quality control standards, executing preventative maintenance of instrumentation, and ensuring strict adherence to established standard operating procedures (SOPs).Familiarity with LIMS/ELN systems.

Education & Competencies (Technical and Behavioral):

Master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences or related discipline with 3+ years OR Bachelor’s degree with 5+ years of relevant industry experience in drug discovery (pharma/biotech).Demonstrated expertise in:High-throughput MS platforms (Acoustic MS, RapidFire MS, MALDI-MS or other platforms)Method development, optimization, troubleshooting and routine operationExperience working within DMTA-driven discovery workflows.Proficiency with MS data analysis tools and software; experience with scripting or data handling (e.g., Python, R, Spotfire) is a plus.Familiarity with laboratory automation systems.Excellent organizational and communication skills.Proven experience in developing and/or evaluating novel small molecule and biologics.Demonstrated ability to work independently and collaboratively in a highly matrixed, cross-functional environment while managing multiple priorities.Stays current with emerging scientific literature, competitive landscapes, and innovative technologies

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$103,500.00 - $162,690.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Senior Scientist will play a pivotal role in Takeda’s “Lab of the Future” initiative, building a capability to provide robust cell lines, at scale, to enable the execution of robust cellular assays on fully automated, integrated platforms. The Senior Scientist will partner closely with Drug Discovery Units (DDUs), Lead Profiling, and automation engineering to help design, build and leverage an automated infrastructure to supply cells to scientists running assays to drive Takeda’s DMTA cycle. In this role you will:

Accelerate Discovery through Automation and AI-Integrated DMTA: Support the design and execution of cellular assays in 384- and 1,536-well formats on fully automated, robotic platforms with robust processes to ensure delivery of consistent cells through continuous culture or cryopreservation.Help create an infrastructure that operates in a highly efficient way, leveraging state-of-the-art automation and technology.Drives Cross-Functional Impact: Partners with DDUs, Lead Profiling, and data science teams to interpret cellular data in the context of SAR, disease biology, and mechanism-of-action, informing compound progression and portfolio decisions.

Accountabilities:

Advance Automated Cell Culture

Design, develop, optimize, and validate cellular automation platforms to enable continuous culture and large-scale cell banks.Partner with assay designers to drive assay miniaturization to 1,536-well formats, ensuring robustness, reproducibility, and biological relevance.

Drive Quality and Efficiency

Ensure that all cell lines are appropriately QC’d and banked.Leverage automation to minimize manual culture and support an assay environment that runs 24/7Ensure that the most disease relevant cells lines are used to drive SARContribute to seamless integration of instrumentation with LIMS/ELN systems, scheduling software, and digital data pipelines to enable end-to-end automation.

Ensure Data Excellence & AI-Readiness

Apply advanced statistical analysis and visualization tools to assess assay robustness, variability, and data quality.Ensure datasets are standardized, curated, and appropriately annotated to support AI/ML-driven analytics and cross-program insights.Contribute to data governance practices that promote longitudinal learning across Takeda’s discovery portfolio.

Collaborate Across Takeda

Partner closely with DDUs, data sciences, translational sciences, and medicinal chemistry to advance program objectives.Communicate findings clearly in cross-functional forums and contribute to scientific discussions that shape portfolio decisions.Uphold Takeda’s values of Integrity, Fairness, Honesty, and Perseverance in all scientific and operational activities.

Education & Competencies (Technical and Behavioral):

Ph.D. in Cell Biology, Pharmacology, Oncology, Molecular Biology, Chemical Biology, or related discipline with at least 2+ years of industry experience ORM.S. with 8+ years; OR B.S. with 10+ years of relevant pharmaceutical or biotech R&D experience.Expert in cell culture, biobanking and cell line maintenanceSignificant experience in building and leveraging cell culture automation to support high throughput workflowsFamiliarity with developing, optimizing, and executing High Content Assays, and other assay modalities such as reporter gene, CTG, GPCR, HTRF, AlphaScreen, MSD, and qPCR for primary, secondary, and mechanistic profiling.Experience embedding AI/ML and advanced analytics into DMTA processes and decision-makingHands-on familiarity with scheduling software, LIMS/ELN, and data pipeline tools commonly used in automated labs.Proficiency in data analysis and figure generation using tools such as Dotmatics, Spotfire or GraphPad.Demonstrated ability to work independently and collaboratively in a highly matrixed, cross-functional environment while managing multiple priorities and contribute to mentoring or guiding junior scientific staff.

Proven track record of:

Hands-on experience with live-cell imaging platforms such as Incucyte for real-time monitoring of cell growth, morphology, and confluence kinetics.Design and implementation of cellular profiling workflows to track growth kinetics, passage number effects, and phenotypic drift over time.Deep understanding of media formulation, optimization, and supplementation strategies to support diverse cell types (primary, iPSC-derived, engineered lines).Experience establishing and maintaining automated cell expansion, passaging, and seeding workflows with tight control over cell health and consistency.

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Objective / Purpose:

The Head of Strategic Research Outsourcing serves as the enterprise‑level leader responsible for shaping and executing the long‑term external innovation and outsourcing strategy across Research. This role leads the organization’s efforts to design, govern, and optimize a global network of Contract Research Organizations (CROs) to advance Takeda’s discovery and preclinical research portfolio.

Operating at the intersection of science, business strategy, and external partnership management, this leader ensures that Takeda’s outsourced research model is a competitive advantage — enabling scalable innovation, operational excellence, and strategic alignment with evolving research priorities. The role has direct managerial responsibility for the teams overseeing early discovery chemistry, preclinical CRO management, and other outsourced research modalities, ensuring that each team is empowered, high‑performing, and future‑focused.

Accountabilities:

Strategic Leadership & Vision

Develop, own, and continuously refine Takeda’s long-range Strategic Research Outsourcing vision, ensuring alignment with Research, Therapeutic Area, and enterprise priorities.Anticipate emerging industry trends, scientific capabilities, global research hubs, and external innovation models to position Takeda at the forefront of strategic outsourcing.Drive the evolution from transactional vendor management to an integrated, strategic partner ecosystem.Drive Takeda’s CRO ecosystem towards a fully integrated and seamless operation model that will support an agilely enhanced research organization.

CRO Network Strategy & Governance

Architect and oversee a global CRO network covering early discovery chemistry, preclinical research, platform technologies, and emerging scientific capabilities.Establish enterprise‑level governance frameworks and operating models to ensure quality, compliance, efficiency, and scientific excellence.Lead strategic CRO selection based on innovation potential, geographic footprint, scientific strength, risk profile, and alignment with long‑term company objectives.

Partnership Development & Relationship Management

Serve as Takeda’s senior executive interface with strategic CRO partners, fostering collaboration, transparency, and joint long‑term planning.Build high‑level connections between Takeda leadership and CRO executives to strengthen innovation pipelines, capability development, and operational resilience.Negotiate strategic agreements and partnership roadmaps that enhance Takeda’s scientific agility and competitive positioning.

Portfolio & Scientific Integration

Ensure outsourced capabilities are best‑in‑class, scalable, and tightly integrated into internal research workflows.Collaborate with scientific leaders to identify capability gaps and determine when externalization is the optimal path.Oversee the scientific and operational performance of CROs, ensuring high‑quality data, timely delivery, and alignment with disease‑area strategies.

Risk Management & Operational Excellence

Identify strategic risks across the CRO ecosystem — including IP protection, dependency risks, geographic concentration, and business continuity — and lead mitigation strategies.Establish KPIs and performance frameworks that evaluate CROs on both operational and strategic dimensions.Drive continuous improvement efforts that enhance productivity, scientific innovation, and cost‑effectiveness.

Team Leadership & Organizational Development

Lead, develop, coach and inspire the leaders and teams responsible for CRO management across chemistry, preclinical research, and future outsourced modalities.Foster a culture of innovation, accountability, cross‑functional collaboration, and external‑ready execution.Build organizational capabilities required for next‑generation outsourced research (e.g., digital integration, data transparency, advanced analytics, new modality CRO ecosystems).Participate as member of the Strategic Operations Leadership Team.

Education & Competencies (Technical and Behavioral):

Education

Advanced degree (Ph.D. strongly preferred) in Chemistry, Life Sciences, or a related scientific discipline; MBA or equivalent business training is an asset.

Experience

12–15+ years of pharmaceutical/biotech R&D experience, including extensive leadership experience managing outsourced research or strategic partnerships.Demonstrated success designing and executing large‑scale outsourcing strategies across discovery or preclinical research.Prior responsibility for managing scientific teams and external partners across global geographies.

Technical Competencies

Deep understanding of discovery and preclinical R&D workflows, including externalized chemistry, pharmacology, DMPK, and related CRO capabilities.Expertise in vendor strategy, scientific operations, governance models, and partnership frameworks.Strong command of strategic planning, risk assessment, contracting, and performance management.

Behavioral Competencies

Strategic thinker capable of shaping long‑term vision and driving enterprise‑level transformation.Exceptional enterprise and matrix leadership, negotiation, and relationship‑building skills.Highly collaborative, with the ability to influence senior stakeholders and navigate matrixed environments.Strong communication skills and the ability to translate complex scientific and business concepts for diverse audiences.Demonstrated ability to manage multiple high‑stakes initiatives simultaneously and guide teams through ambiguity.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$212,000.00 - $333,190.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Senior Scientist will play a pivotal role in Takeda’s “Lab of the Future” initiative, driving the design, miniaturization, and execution of robust cellular assays on fully automated, integrated platforms. Leveraging advanced automation systems and statistical analysis, this individual will ensure high-throughput, reproducible, and high-quality data generation to support iterative AI-integrated Design–Make–Test–Analyze (DMTA) cycles for both small- and large-molecule discovery. The Senior Scientist will partner closely with Drug Discovery Units (DDUs), chemistry, data sciences, and automation engineering to translate complex cellular data into actionable insights that accelerate portfolio progression and enable data-driven decision-making. This role contributes to critical function delivery as follows:

Accelerates Discovery through Automation and AI-Integrated DMTA: Designs and executes cellular assays in 384- and 1,536-well formats on fully automated, robotic platforms with integrated workflows, enabling rapid, high-throughput testing and iterative optimization.Ensures Data Quality and Scientific Rigor: Applies statistical methodologies to evaluate assay performance (e.g., Z’ factor, S/B, curve-fit confidence) and maintains reproducibility and reliability of decision-enabling datasets.Drives Cross-Functional Impact: Partners with DDUs, chemistry, and data science teams to interpret cellular data in the context of SAR, disease biology, and mechanism-of-action, informing compound progression and portfolio decisions.

Accountabilities:

                                                                                                

Advance Automated Cellular Lead Profiling

Design, develop, optimize, and validate disease-relevant cellular assays supporting hit identification, hit-to-lead, and lead optimization programs in oncology and gastrointestinal diseases.Drive assay miniaturization to 384- and 1,536-well formats, ensuring robustness, reproducibility, and biological relevance.Implement statistically rigorous assay performance standards (e.g., Z’ factor, signal-to-background, CV, curve-fit quality metrics) to ensure data integrity and confidence in decision-making.

Enable Efficient DMTA Cycles

Deliver timely IC50 determinations and mechanistic cellular data to support iterative DMTA cycles across small- and large-molecule modalities.Interpret cellular data in the context of SAR, disease biology, and target mechanism to inform compound progression.Continuously improve workflows to shorten cycle times and increase throughput while maintaining quality.

Operate Within Fully Integrated, Automated Systems

Develop and execute assays on fully automated robotic platforms, including liquid handling systems, acoustic dispensing, high-content imaging, and multimode detection technologies.Partner with automation engineers to design scalable, modular workflows aligned with Lab of the Future principles.Contribute to seamless integration of instrumentation with LIMS/ELN systems, scheduling software, and digital data pipelines to enable end-to-end automation.

Ensure Data Excellence & AI-Readiness

Apply advanced statistical analysis and visualization tools to assess assay robustness, variability, and data quality.Ensure datasets are standardized, curated, and appropriately annotated to support AI/ML-driven analytics and cross-program insights.Contribute to data governance practices that promote longitudinal learning across Takeda’s discovery portfolio.

Collaborate Across Takeda

Partner closely with DDUs, data sciences, translational sciences, and medicinal chemistry to advance program objectives.Communicate findings clearly in cross-functional forums and contribute to scientific discussions that shape portfolio decisions.Uphold Takeda’s values of Integrity, Fairness, Honesty, and Perseverance in all scientific and operational activities.

Education & Competencies (Technical and Behavioral):

Expected: Ph.D. in Cell Biology, Pharmacology, Oncology, Gastroenterology, Chemical Biology, or related discipline with at least 2+ years of industry experience; OR M.S. with 8+ years; OR B.S. with 10+ years of relevant experience in pharmaceutical or biotech R&D.Hands-on experience developing, optimizing, and executing High Content Assays (HCA), with strong experience in GPCR and ion channel assay development and screening, and familiarity with assay modalities such as reporter gene, CTG, HTRF, AlphaScreen, NanoBRET, HiBiT, MSD, and qPCR for primary, secondary, and mechanistic profiling.Experience in hit-to-lead and lead optimization support, including interpreting cellular data in the context of SAR and portfolio strategy.Working knowledge of integrated HTS automation systems and robotic platforms, including programming, configuring, and troubleshooting liquid handlers (e.g., Echo, Hamilton, Beckman, Agilent).Experience embedding AI/ML and advanced analytics into DMTA processes and decision-makingHands-on familiarity with scheduling software, LIMS/ELN, and data pipeline tools commonly used in automated labs.Proficiency in data analysis and figure generation using tools such as Dotmatics, Spotfire or GraphPad.Demonstrated ability to work independently and collaboratively in a highly matrixed, cross-functional environment while managing multiple priorities and contribute to mentoring or guiding junior scientific staff.

Proven track record of:

Developing and validating cellular assays for drug discovery.Demonstrated strong experience in GPCR and ion channel assay development and screening, including hands-on expertise with FLIPR system platforms and automated patch-clamp technologies such as SyncroPatch 384PE in at least 384-well high-throughput formats.Proven experience working with small-molecule compound or CRISPR libraries in high-throughput screening (HTS) and lead optimization contexts.Strong statistical and analytical skills for assay quality assessment, including Z’, CV, signal-to-background, and curve-fit confidence.Running assays on fully automated, robotic platforms in high-throughput environments.Successful miniaturization of assays to at least 384-well and preferably 1,536-well plate formats.

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA. 

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

About the Role:

At Takeda, we are guided by our purpose of Better Health for People, Brighter Future for the World and our commitment to patients, our people, and the planet. Leading smooth transitions and integration of labs, systems, processes, and capabilities is essential to maintaining operational continuity and delivering on our commitments to patients, regulators, and partners.

We are seeking an Executive Director, Head of Lab Operations to lead and scale global laboratory operations across Takeda’s R&D organization. This role is responsible for ensuring that lab environments, processes, and systems are optimized to enable scientific excellence, operational efficiency, and scalability across a complex global footprint.

You will operate at the intersection of science, operations, and strategy—driving large-scale operational excellence initiatives, enabling scientists to focus on discovery, and shaping the future of laboratory operations, including preparation for the One Cambridge Campus.

What You Will Do:

As a key leader in the R&D Operational Excellence organization, you will:

Lead and oversee global R&D laboratory operations, defining standardized processes, roles, and governance while enabling best practice sharing across regions and appropriate local adaptation.

Develop and execute enterprise laboratory operations strategies to centrally scale and optimize services across R&D, increasing productivity and reducing administrative burden on scientific teams.

Ensure end-to-end operational support for R&D laboratories, including equipment, space, utilities, purchasing, maintenance, calibration, and materials flow, enabling scientific teams to focus on technical execution.

Drive R&D laboratory space and capacity strategy, including long term planning and readiness for the One Cambridge Campus, lab footprint scaling, asset utilization, storage, and materials flow optimization.

Coordinate global laboratory operations services and partnerships, serving as a primary interface for vendors and lab users; oversee CAPEX and OPEX, performance metrics, and continuous improvement, including innovation in automation, robotics, AI/data integration, and asset sharing.

Serve as the central R&D point of accountability for lab operations, including safety/EHS, procurement, and compliance, with clear escalation and issue resolution mechanisms to protect program timelines and support R&D simplicity goals.

What Makes This Role Unique:

This role sits at the center of enabling scientific innovation by ensuring that laboratory environments operate efficiently, consistently, and at scale across a complex global footprint. You will:

Lead high-visibility, enterprise-critical initiatives that shape the future of Takeda’s R&D laboratory operations.

Drive large-scale transformation in preparation for the One Cambridge Campus and evolving global lab strategy.

Balance the needs of scientists with operational efficiency, enabling productivity while simplifying processes.

Serve as a key partner across R&D and with external vendors, influencing how laboratory operations evolve globally.

Success in this role requires a leader who can balance strategic vision with operational execution and people leadership, while influencing across a highly matrixed, global organization.

What You Bring:

Deep experience in pharmaceutical R&D environments, including strong understanding of laboratory operations and processes.

Proven experience leading large-scale lab operations, including equipment, facilities, procurement, maintenance, and vendor management.

Strong experience driving operational efficiency, process improvement, and implementation of new systems.

Experience managing large-scale financial oversight, including CAPEX and OPEX budgets.

Strong understanding of safety, compliance, and regulatory considerations within laboratory environments.

Ability to think strategically while operating at a practical, execution-focused level, even in ambiguous situations.

Leadership & Impact:

Demonstrated ability to lead complex global organizations and drive operational and cultural change, both directly and through influence.

Strong leadership presence with the ability to influence, align, and inspire across functions, regions, and levels.

Proven ability to lead transformation initiatives, implement new systems, and drive process changes.

Ability to establish alignment through collaboration and persuasive communication; strong communicator with excellent written, verbal, and presentation skills.

Ability to influence and work effectively across business partnerships, regions, and cultures while balancing scientific needs with operational efficiencies.

Education & Experience:

Bachelor’s degree in life sciences, pharmacy, engineering, operations, business management, or related field.

15+ years of experience in pharmaceutical R&D, with a preference for lab operations management & leadership, and deep experience working with scientists, vendor management and procurement functions in an R&D lab environment.

Minimum 7 years of people leadership experience, including driving process change and implementing systems.

Experience working within complex, matrixed organizations across functions and regions.

Proven track record of leading large-scale lab operations, driving organizational change, and delivering complex programs.

Preferred:

Advanced degree in science or business.

Certifications in operational excellence, vendor management, or process improvement programs.

Additional Information:

Requires approximately 10–15% travel, including domestic and international travel.

Flexibility to support meetings across global time zones.

This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$238,000.00 - $374,000.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Objective / Purpose:

Takeda’s Lead Profiling team is building a new team of experienced, innovative, and collaborative researchers to partner with Drug Discovery Units to design and run high throughput automated assays on state-of-the-art robotic platforms to drive an industry-leading portfolio of drugs for various Therapeutic areas with high unmet medical needs. We are seeking a skilled research Senior Scientist to join our Lead Profiling and cross-functional discovery teams.

Design and execute pre-clinical pharmacology assays on fully automated robotic platforms to support candidate selection, accelerating clinical translation of impactful therapies for patients with various disordersProvide deep scientific expertise in the design and execution of miniaturized, high throughput assays to support programs across cross-functional teamsLeverage state-of-the-art automation to streamline complex biology screening workflows and manage data across various programs, in close collaboration with Takeda scientists and external partners

Accountabilities:                                                                                                  

Lead the design, development, and validation of robust plate-based miniaturized (384 and 1536-well) biochemical assays (e.g., enzyme, binding, target engagement assays) to facilitate compound screening, characterization, and mechanistic profiling to support medicinal chemistry SAR efforts.Develop and implement fully automated screening workflows to support multiple programs in the discovery portfolioChampion scientific integrity and rigor in data analysis, preparation, and interpretation of detailed protocols/SOPs.Lead the adoption of advanced analytics, modeling, and AI/ML approaches to inform assay design, hit triage, SAR development, and portfolio decisions. Contribute to the establishment of data standards and governance for biochemical lead profiling, enabling longitudinal data mining and cross-program learningCollaborate effectively within a matrixed structure, clearly communicate results, challenges, and impact through presentations and discussions with broad audiences.  Integrate data from cross-functional teams to drive decision-making.Think independently and creatively to explore novel drug discovery approaches to create therapies for patients suffering from disorders being investigated within Takeda discovery research.Maintain awareness of current developments in literature and contribute to the continuous process to enhance functional capability and productivitySupport the organization by maintaining a work environment focused on scientific integrity, continuous learning, open communication, and collaborationMentorship and coaching of other scientists within the team to create and sustain a high-performing team

Education & Competencies (Technical and Behavioral):

Expected: PhD degree in Biochemistry, Biophysics, Pharmacology, Molecular/Cell Biology or related field with 2+ years industry experience, or MS with 8+ years’ experience, or BS with 10+ years of relevant experience in pharmaceutical/ biotech R&D.Strong expertise, in-depth knowledge and hands-on experience in the development and optimization of a wide range of assays and screening technologies (e.g., Fluorecence, AlphaLISA, TR-FRET, ELISA, target engagement, residence time measurements etc).Working knowledge of HTS automation, liquid handling systems and assay miniaturization to streamline workflowsStrong expertise is Lead ID, Hit-to-Lead and Lead Op strategies and workflows is highly desirableSignificant experience leveraging high throughput data analysis platforms and LIMS systems for automated data analysis, QC and reportingStrong enzymology background preferredProven experience in developing and/or evaluating novel small molecule and biologicsStays current with emerging scientific literature, competitive landscapes, and innovative technologies to contribute to the continuous process to enhance functional capability and productivityAbility to collaborate in a multidisciplinary and dynamic environment, and experience in mentoring and leading other scientific staff

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsBoston, MA

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Read Less