The Wistar Institute has an opening for a highly motivated Research Assistant to work in the laboratory of Dr. Murad Mamedov as part of the new Center for Advanced Therapeutics at The Wistar Institute. The Mamedov Lab uses large-scale CRISPR screens and functional genomics to understand how the human immune system detects and kills cancerous and other diseased cells. We focus on human γδ T cells and other unconventional T cells, studying how these immune cells sense cellular stress in tumors, with the goal of developing novel and broadly accessible immunotherapies. The successful candidate will receive personalized training and close mentorship. High-performing candidates will have opportunities to expand responsibilities, develop new technical strengths, and contribute meaningfully to publications and presentations.
What You Will Do
A wide variety of experiments and tasks, including:Performing large-scale CRISPR screens and gene editing/engineeringRunning cell culture assays with cell lines and primary human samples, including whole bloodExecute molecular biology workflows (e.g. PCR/qPCR, cloning, DNA/RNA work)Collect, organize, and summarize data, maintaining rigorous notesSupport lab operations: inventory management, ordering, reagent/consumables tracking, and general lab organizationCommunicate progress clearly in a collaborative team setting (lab meetings, one-on-one meetings, shared planning)
Required Qualifications
Bachelor's degree in a science-related field (or equivalent combination of education and experience)Excellent attention to detail, organization, and reliability with hands-on experimental workClear communication skills and a collaborative mindsetHigh motivation to learn, improve, and take ownership of high-quality work
Preferred Qualifications
Cell cultureFlow cytometryMolecular biology (PCR, cloning, sequencing library work)Lentivirus or other viral vector productionNext-generation sequencingPrior full-time research experience (academic or industry)
To apply, please submit:
Curriculum vitaeContact information for 2-3 referencesA short cover letter describing your research interests and fit (optional).
The Wistar Institute is a world leader in early-stage discovery science in the areas of cancer, immunology, and infectious disease. Wistar is committed to accelerating research advances from bench to bedside through brilliant science and distinctive approaches to collaboration among scientific investigators and academic and industry partners. Wistar's dynamic environment supports the advancement of discoveries that will change the future of human health.
The Wistar Institute is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities.
We offer a competitive salary and excellent benefits package.
For more information about The Wistar Institute visit our website at www.wistar.org.
It is the policy of the Institute to provide equal employment opportunities to all individuals regardless of race, citizenship, ethnicity, color, creed, religion, marital status, national origin, ancestry, sex, age, veteran status, mental or physical disability (including HIV and AIDS), pregnancy, caregiver status, domestic or sexual violence victim status, sexual orientation, gender identity and expression, or on the basis of genetic information, or any other characteristic protected by federal, state, or local law, with respect to all terms and conditions of employment.
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