Natera is seeking a Senior Bioinformatics Scientist to lead the architecture, development, and automation of high-throughput genomic pipelines. This role is responsible for building production-grade software tools to analyze next-generation sequencing (NGS) data including variant calling, fusion detection, and data quality control. The ideal candidate combines a deep understanding of sequence alignment algorithms with strong object-oriented programming skills to design scalable computational workflows in a fast-paced, mission-driven environment.
Primary Responsibilities:
Analyze complex genomic datasets leveraging scaled in-house pipelines, partnering cross-functionally with wet-lab scientists and statisticians to rapidly deliver data-driven answers to critical research goals.Architect, build, and deploy automated analysis pipelines for diagnostic tests, integrating robust capabilities for fusion detection, variant calling, and automated quality control metrics.Engineer novel genomic analysis tools and proactively identify optimization pathways to enhance pipeline accuracy and efficiency.Participate in code reviews, technical documentation, and the continuous improvement of core computational workflows.Coordinate directly with downstream infrastructure teams to ensure R&D tools scale efficiently into production systems.Qualifications:
Ph.D. or Master's degree with a minimum of 5 years of professional experience in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field.Knowledge, Skills, and Abilities:
Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows.Advanced understanding of data structures, algorithm design, and computational complexity.Strong software engineering proficiency in Java or C++ within a professional production environment.Demonstrated scripting capability in Python or Perl for data manipulation, automation, and rapid prototyping.Deep expertise navigating Linux environments, utilizing command-line tools, and writing efficient shell scripts.Prior experience working with relational databases, particularly MySQL, is highly desirable.Demonstrated technical autonomy and rigorous data discipline when troubleshooting high-complexity algorithmic challenges.Excellent communication skills with a proven track record of explaining computational results clearly to cross-functional stakeholders.The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$117,400—$146,800 USDOUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
Natera is seeking a Senior Bioinformatics Scientist to lead the architecture, development, and automation of high-throughput genomic pipelines. This role is responsible for building production-grade software tools to analyze next-generation sequencing (NGS) data including variant calling, fusion detection, and data quality control. The ideal candidate combines a deep understanding of sequence alignment algorithms with strong object-oriented programming skills to design scalable computational workflows in a fast-paced, mission-driven environment.
Primary Responsibilities:
Analyze complex genomic datasets leveraging scaled in-house pipelines, partnering cross-functionally with wet-lab scientists and statisticians to rapidly deliver data-driven answers to critical research goals.Architect, build, and deploy automated analysis pipelines for diagnostic tests, integrating robust capabilities for fusion detection, variant calling, and automated quality control metrics.Engineer novel genomic analysis tools and proactively identify optimization pathways to enhance pipeline accuracy and efficiency.Participate in code reviews, technical documentation, and the continuous improvement of core computational workflows.Coordinate directly with downstream infrastructure teams to ensure R&D tools scale efficiently into production systems.Qualifications:
Ph.D. or Master's degree with a minimum of 5 years of professional experience in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field.Knowledge, Skills, and Abilities:
Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows.Advanced understanding of data structures, algorithm design, and computational complexity.Strong software engineering proficiency in Java or C++ within a professional production environment.Demonstrated scripting capability in Python or Perl for data manipulation, automation, and rapid prototyping.Deep expertise navigating Linux environments, utilizing command-line tools, and writing efficient shell scripts.Prior experience working with relational databases, particularly MySQL, is highly desirable.Demonstrated technical autonomy and rigorous data discipline when troubleshooting high-complexity algorithmic challenges.Excellent communication skills with a proven track record of explaining computational results clearly to cross-functional stakeholders.Compensation & Total Rewards
This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
Compensation Range $130,700—$163,400 USDOUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
POSITION SUMMARY:
Join Natera's Bio Development team as an Associate Scientist to design, optimize, and validate molecular assays for our market-leading non-invasive prenatal testing (NIPT) platform. This role bridges molecular biology with high-throughput liquid handling automation to directly impact patient care. The ideal candidate possesses strong experience in assay development, automated workflows, and data analysis, operating with an ownership mindset to convert scientific data into scalable clinical protocols.
PRIMARY RESPONSIBILITIES:
Design, plan, and execute complex laboratory experiments autonomously to advance non-invasive prenatal test developmentAnalyze experimental data using advanced analytical tools, providing data-driven insights and troubleshooting laboratory processesOwn and document technical workflows, summarizing findings in research reports and laboratory presentationsPartner cross-functionally with Clinical Laboratory Operations (CLIA), Quality Assurance (QA), and Automation Engineering to ensure methods meet rigorous quality and regulatory standardsWrite standard operating procedures (SOPs) and technical documentation to seamlessly transfer protocols to manufacturing and operations teamsTrain junior team members and operator teams on newly developed protocolsMaintain deep professional expertise by staying current with scientific literature relevant to cell-free DNA and nucleic acid technologiesQUALIFICATIONS:
BA/BS with 6+ years of experience OR MS with 3+ years of experience in assay development and automation within the life sciences industryDemonstrated track record of developing, optimizing, and validating manual and automated protocolsKNOWLEDGE, SKILLS, AND ABILITIES:
Strong underlying scientific knowledge of nucleic acid extraction, PCR, NGS library preparation, and hybrid capture technologiesHands-on experience in reagent preparation and quality control for NGS-associated assaysDirect experience implementing, optimizing, and troubleshooting high-throughput automated assays utilizing liquid handler roboticsExperience designing and executing formal design control studies, including stability, guard banding, reproducibility, repeatability, and validationPrior experience operating within a regulated laboratory environment (CLIA, CAP, or FDA)Data analysis and scripting proficiency in Python or R, along with liquid handler programming experience, is highly preferredExcellent cross-functional collaboration, organizational, and time management skillsThe pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Austin, TX$84,000—$105,000 USDOUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
